Uncommon reported complications of EUS-FNA for pancreatic tumour PF-02341066 ic50 were infection, bleeding, perforation, and acute pancreatitis. Acute portal vein thrombosis (APVT) as rare complication of EUS-FNA was reported once only in a case of advance metastatic pancreatic cancer. Local tumour infiltration of portal vein with post EUS-FNA bacteremia

was presumably the causative factors and intravenous antibiotic prior to EUS-FNA was suggested as preventive measures. Methods: We present a middle age lady with advance metastatic pancreatic cancer referred for EUS-FNA. Preprocedural imaging studies showed a pancreatic head mass, measuring 3.8 x 3.3 cm with

thick enhancing wall and central hypodensity. The portovenous and splenomesenteric vessels were patent. Several hepatic masses were noted, in keeping with metastases. Antibiotic was given to the patient in view of cystic nature of pancreatic tumour prior to EUS_FNA. The EUS-FNA was performed with linear endoscopic ultrasound (Olympus, GF-UCT140-AL5, Japan). EUS-FNA was performed on the lymph node initially, and followed by pancreatic tumour with 22 G FNA needle (Cook Medical Inc, Limerick Ireland). The pancareatic tumour was difficult to assess despite changing to pancreatic tumour with 25 G FNA EPZ015666 ic50 needle (Cook Medical Inc, Limerick Ireland). The technical difficulty in assessing the lesion led to prolonged procedural time. Results: She presented three days later with abdominal pain, which later diagnosed as acute portovenous thrombosis based on repeated computer tomogram. Anticoagulation was initiated and subsequently patient was arranged for palliative chemotherapy. Conclusion: In conclusion, medchemexpress prothrombotic state in advance pancreatic cancer, venous stasis from endoscope manipulation and micro-endothelial injury from mechanical manipulation during EUS-FNA can lead

to acute portal vein thrombosis. Our experience showed acute portal vein thrombosis can occur in naïve portovenous vessels in advanced pancreatic cancer. Key Word(s): 1. Portal Vein; 2. Thrombosis; 3. Endoscopy; 4. Ultrasound; Presenting Author: HIROYUKI HISAI Additional Authors: YUTAKA KOSHIBA, TASUKU HIRAKO, YUUKI IKEDA, YOHEI ARIHARA, ETSU MIYAZAKI Corresponding Author: HIROYUKI HISAI Affiliations: Jaoan Red Cross Date General Hospital Objective: The aim of the current study was to evaluate the effectiveness of emergency ERCP and pancreatic duct (PD) stent placement in patients with acute biliary pancreatitis (ABP). Methods: Between January 2002 and March 2013, 90 patients with ABP referred to our institution. Total 60 consecutive patients were enrolled in the study.