A right- anterior oblique (RAO) view is generally recommended to evaluate esophageal morphology, but some achalasia patients show more pronounced meandering buy Carfilzomib of the esophagus in the left anterior oblique (LAO) view. To evaluate the usefulness of LAO views for esophagography, we investigated differences of esophageal dilatation and meandering between RAO and LAO images. Methods: From April to September 2013, 11 achalasia patients aged 59.4 ± 17.3 yrs (mean ± SD, including eight new patients and three with recurrence,

underwent esophagography for dysphagia and were enrolled. In the new patients, achalasia was diagnosed by high resolution esophageal manometry (ManoScan, USA), and was classified as type I in 2 patients and type II in 6 accoding to Chicago classification. RAO and LAO views were obtained at 1 minute after swallowing 100 ml of 125% barium sulfate in the standing position, and the maximum transverse Depsipeptide diameter and the angle at which the major esophageal

axes intersect were compared. Results: The maximum transverse diameter (mean ± SE) was 41.7 ± 4.3 cm on RAO images and 45.2 ± 4.6 cm on LAO images. The angle of intersection of the major axes (mean ± SE) was 154.0 ± 5.4°on RAO images and 131.8 ± 5.8°on LAO images. Although there were no significant differences of the angle of intersection and esophageal diameter, the angle was smaller on LAO images than MCE RAO images in two patients (18.1%).

Conclusion: Two of 11 patients showed greater meandering on LAO views compared with RAO views, although there were no statistical differences. These findings suggest that adding LAO views to RAO views for esophagography is useful to evaluate esophageal morphology in achalasia patients. Key Word(s): 1. Achalasia; 2. esophagogpraphy; 3. LAO (left anterior position) Presenting Author: IL HYUN BAEK Additional Authors: NA Corresponding Author: IL HYUN BAEK Affiliations: Na Objective: Background: Recently, variable gastrointestinal track tumors including early stage malignancies are treated by endoscopic procedure. A preoperative histologic diagnosis of neoplasia is a requirement for endoscopic submucosal dissection (ESD). However, the discrepancy of histologic diagnosis may sometimes occur between the pretreatment forceps biopsy specimens versus versus ESD specimens. In this study, we wanted to investigate of discrepancy rate between the histology of the endoscopic biopsy and that of the resected specimen obtained from the same lesion by endoscopic submucosal dissection (ESD) in the Korean population.