Conclusions: Translation of the IPQ-R has good reliability and similar structure to that of the original. Difficulties to confirm the structure of Causal Representations
may represent cultural differences in understanding illness causation. Copyright (C) 2009 John Wiley & Sons, Ltd.”
“Objective: To determine the efficacy of topical mitomycin and stenting in patients that have undergone endoscopic repair of choanal atresia.
Methods: Retrospective review of 37 endoscopic operations on pediatric patients for choanal atresia.
Results: Twenty-six sides were operated on in 17 patients; 37 total operations were performed. All 17 patients were repaired endoscopically with I patient requiring buy AZD2014 transpalatal revision surgery. Eight patients (47%) had a unilateral atresia and 9 (53%) were bilateral. Eleven total sides (42%) were treated initially with mitomycin. Eighteen percent of those sides required
post-operative dilation vs. 40% of the sides not treated with mitomycin (p = 0.39) and no patient in the mitomycin group required revision surgery compared to 20% of patients not treated with mitomycin (p = 0.24). Significantly fewer sides in the mitomycin MCC950 mw group (9%) developed granulation vs. those treated without (53%) (p = 0.03). The average number of procedures performed (1.18 vs. 2.53; p = 0.002) was significantly fewer in those patients treated with mitomycin vs. not. A greater amount of sides in the stent group developed granulation tissue (50% vs.0%; p = 0.023). The average number of procedures performed was significantly greater in those patients treated with a stent (2.33 vs. 1.12; p = 0.008). The average time spent in compound inhibitor the hospital was significantly shorter (7.09 vs. 2.33 days; p = 0.02) in those patients treated without stenting.
Conclusion: Topical mitomycin is efficacious as an adjuvant therapy as it was
associated with the formation of less granulation tissue, a lower rate of restenosis and fewer surgeries. Stenting was associated with significantly more procedures, greater formation of granulation tissue and longer overall hospital stays. However, consideration should be given toward stent placement in all neonates for the prevention of post-operative airway obstruction.
Level of evidence: 2c. (C) 2013 Elsevier Ireland Ltd. All rights reserved.”
“Studies on different populations have suggested variability in individual susceptibility to altitude sickness depending on genetic makeup. The renin-angiotensin-aldosterone system (RAAS) pathway plays a key role in regulation of vascular tone and circulatory homeostasis. The present study was undertaken to investigate the possible association of the RAAS in the development of high-altitude pulmonary edema (HAPE) in lowlanders exposed to high altitude.