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“Objective: To evaluate the ability of hypoglossal-facial C59 Wnt ic50 nerve anastomosis to reanimate the face in patients with complete nuclear (central) facial nerve palsy.

Study Design: Retrospective case series.

Setting: Tertiary academic medical center.

Patients: Four patients with complete facial nerve paralysis due to lesions of the facial nucleus in the pons caused by hemorrhage due to arteriovenous or cavernous venous malformations, stroke, or injury

after tumor resection.

Intervention: All patients underwent end-to-end hypoglossal-facial nerve anastomosis.

Main Outcome Measures: Facial nerve function using the House-Brackmann (HB) scale and physical and social/well-being function using the facial disability index.

Results: The mean age of the patients was 53.3 years (range, 32-73). There were 3 female and 1 male patients. All patients had preoperative facial function HB VI/VI. With a minimum of 12 months’ follow-up after end-to-end hypoglossal-facial anastomosis, 75% of patients regained function to HB grade III/VI, and 25% had HB grade IV/VI. Average facial disability index scores were 61.25 for physical function and 78 for social/well-being, comparable to results from complete hypoglossal-facial anastomosis after peripheral facial nerve

palsy after acoustic neuroma resection.

Conclusion: Patients with nuclear facial paralysis who undergo end-to-end hypoglossal-facial nerve anastomosis achieve LY2603618 price similar degrees of reanimation compared with those with peripheral facial nerve palsies. This raises the intriguing possibility that reinnervation may also be of benefit in patients with the vastly more

common facial dysfunction because of cortical stroke or injury.”
“Moyamoya syndrome is a progressive occlusive disease of the cerebral vessels. There are a variety of surgical treatments directed at revascularizing the ischemic brain in pediatric moyamoya disease. Many reports of varying success with both direct and indirect type of procedures can be found in medical literature. We present a novel technique, encephalo-TPF-synangiosis (ETS) with a pedicled bone flap, for indirect moyamoya revascularization in pediatric patients. A three-quarters osteoplastic temporal craniotomy was created. A pedicled temporoparietal fascial flap was passed intracranially this website through the temporalis muscle and placed into contact with the pial surface. The bone flap was the reaffixed to the skull. We performed 8 ETS in 6 patients. This is a well-vascularized, highly reliable method that offers broad-based surface area for revascularization. We also offer a composite overview of current surgical indirect revascularization techniques.”
“The outcome of patients with aspergilloma undergoing lung transplantation is not completely known, but anecdotal reports of poor outcome after transplant have discouraged this practice.