PubMedCrossRef 36. Cilloni D, Messa F, Gottardi E, Fava M, Arruga F, Defilippi I, Carturan S, Messa E, Morotti A, Giugliano E, Rege-Cambrin G, Alberti D, Baccarani M, Saglio G: Sensitivity

to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation. Cancer 2004, 101:979–988.PubMedCrossRef Competing interests The authors declare that they have no competing interests. Authors’ Ganetespib contributions SMG and CYX contributed to clinical data, samples collection, CCK8, qRT-PCR and drafted manuscript. CQC carried out Western blotting. SSL carried out plasmids, siRNA, and AMO transfection. PHD carried out Luciferase reporter experiments. FJY performed the study design, statistical analysis, and manuscript writing. All authors read and approved the final manuscript.”
“Introduction Tennis tournaments are quite complex due to their variability in terms of exercise duration and the type of effort required. One feature of competitive tennis is that the GSK1120212 season is relatively long and that the ranking system pushes players to compete all year long. During a competition, buy Alpelisib players must sometimes play one or two matches a day on consecutive days. For many reasons the duration and intensity of these matches are highly variable, but it is not uncommon to see matches continue beyond three hours [1,2] and various studies

have shown a drop in high-level tennis performance during extended matches [3–6]. Under these conditions, optimum recovery methods are needed to maintain a high level of performance over the duration of a match, tournament or season. Among the strategies used, nutrition appears to be an important element to consider [7]. The Glycogen branching enzyme majority of studies on the impact of nutritional strategies on tennis performance have been conducted by taking measurements during or at the end of long matches. Some studies have suggested a beneficial effect of carbohydrates during prolonged tennis matches [4,5,8–10]. Caffeine has also been suggested as positively affecting performance, although the number of relevant studies is very limited [4,5,9]. Among less common nutritional strategies,

one study has also demonstrated a beneficial effect of sodium bicarbonate [6]. On the other hand, creatine supplementation did not appear to lead to positive effects on tennis performance [11,12]. To our knowledge, no study has evaluated the effects of nutritional strategies on physical performance in the days following a series of matches, despite this being the reality of competitive tennis. Furthermore, studies conducted in the field of tennis nutrition have only been interested in the isolated effects of nutritional strategies before or during the match. However, it is increasingly common for competitive athletes to use sports drinks before, during and after matches to help maintain their performance over the duration of a tournament [13].