This difference reached statistical significance at 2 month;: and

lasted to 3 months. No endoleak was detected in either group at the time of sacrifice. Gross analysis confirmed that all the aneurysm sacs were thrombosed without any flow inside the sac.

Conclusion: Despite absence of an endoleak, infra-sac pressure remained high in the STA group. RSA effectively reduced sac pressure over time. Graft porosity appears to be an important factor that may determine the outcome of EVAR. These findings may be useful in designing improved endograft. (J Vase Surg 2009;49:1021-8.)

Clinical Relevance: Our objective was to use an animal model to confirm that type 4 and 5 endoleaks depend on the porosity of the endograft fabric. Our results suggest that low porosity endograft is find more preferable. These findings will also be useful in designing improved aortic endografts.”
“Objective: We developed learn more a novel method using

anatomic markers along the thoracic aorta to accurately quantify longitudinal and circumferential cyclic strain in nondiseased thoracic aortas during the cardiac cycle and to compute age-related changes of the human thoracic aorta.

Methods: Changes in thoracic aorta cyclic strains were quantified using cardiac-gated computed tomography image data of 14 patients (aged 35 to 80 years) with no visible aortic pathology (aneurysms or dissection). We measured the diameter and circumferential cyclic strain in the arch and descending thoracic aorta (DTA), the longitudinal cyclic strain along the DTA, and changes in arch length and motion of the ascending aorta relative to the DTA. Diameters were computed distal to the left coronary artery, proximal and distal to the brachiocephalic trunk, and distal to the left common carotid, left subclavian,

and the first and seventh intercostal selleck chemicals arteries. Cyclic strains were computed using the Green-Lagrange strain tensor. Arch length was defined along the vessel centerline from the left coronary artery to the first intercostal artery. The length of the DTA was defined along the vessel centerline from the first to seventh intercostal artery. Longitudinal cyclic strain was quantified as the difference between the systolic and diastolic DTA lengths divided by the diastolic DTA length. Comparisons were made between seven younger (age, 41 7 years; 5 men) and seven older (age, 68 6 years; 5 men) patients.

Results: The average increase of diameters of the thoracic aorta was 14% with age from the younger to the older (mean age, 41 vs 68 years) group. The average circumferential cyclic strain of the thoracic aorta decreased by 55% with age from the younger to the older group. The longitudinal cyclic strain decreased with age by 50% from the younger to older group (2.0% +/- 0.4% vs 1.0% +/- 1%, P = .03).